During the forecast period, 2019-2024, the exosomes market is expected to register a CAGR of nearly 18.0%.
• Some driving market growth factors include increased cancer incidence, technological advances in exosome isolation and analytical procedures, increased public projects and financing for exosome studies, and increased sophisticated exosome apps.
• The increasing prevalence of patients with cancer has a direct impact on the exosome market s increased demand.
• According to the World Health Organization WHO s 2012 report, there have been 14 million fresh cancer instances, and this is projected to increase by about 70% over the next two decades.
• In the United States, an approximately 1.7 million fresh cancer instances were diagnosed in the nation, according to the 2018 National Cancer Institute study, and nearly 0.6 million people died from cancer.
• Exosomes obtained from cow milk are used against lung and breast cancer for the delivery of therapeutic molecules.
• Because of the increased passive targeting due to its tiny size, native nature, and the capacity to cross biological obstacles, exosomes extracted from particular body locations are promising candidates for anti-cancer medicines. Thus, the rise in hospital cancer instances directly raises the demand for both diagnostic and therapeutic exosomes.
• However, a number of technical problems in successfully implementing exosomes in different apps need to be resolved. This is one of the main obstacles to the exosome market s growth.
• Some of the main challenges include optimizing purification, enhancing exosome homogeneity, and effective techniques for transfection. Furthermore, this is followed by a absence of technical data, such as rotor type, diameter, quantity and sample viscosity, which restricts the maximum use of exosomes.
• The cumbersome nature of isolation/purification techniques and the failure to differentiate between distinct cancer stages with an incomplete knowledge of the immune system restricts the market for exosomes.
• The lack of qualified professionals and stringent regulatory requirements for the approval and marketing of exosome products are other factors that limit the growth of this market.
The Report’s Scope:
Exosomes are tiny membrane vesicles of endocytic origin that are secreted by most culture cells and are formed by the fusion of the multiple endocytic body MVB with the plasma membrane. They are nano-sized vesicles capable of transferring DNAs, micro RNAs, non-coding RNAs, and lipids, with or without direct cell-to-cell contact, representing a novel intracellular communication technique.
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Key Trends of Exosomes Market:
Ultracentrifugation is Anticipated to Hold Significant Market Share in the Isolation Method Segment:
Centrifugation is used to analyze the hydrodynamic properties of polymeric materials such as nucleic acids and proteins, including biopolymers. Ultracentrifugation-based exosome isolation especially differential is considered as the gold standard in isolation methods, which generates exceptionally high centrifugal forces of up to 1,000,000 adjacent g and is one of the commonly used and reported exosome isolation techniques. One of the potential benefits of this method is decreased risk of costs and contamination with separation reagents. It has a big ability for sampling and produces big quantities of exosomes. Drawbacks include big time, unscalable, vesicle chances of damage, and low yield. Global businesses, such as Thermo Fisher Scientific, give a variety of complete exosomal isolation kits that provide reagents for cell culture media, serum, plasma, urine, and other body fluids, including cerebrospinal fluid, ascetic fluid, amniotic fluid, milk, and saliva.
North America Dominates the Market and is Expected to do the Same in the Forecast Period:
The North American area maintains one of the biggest shares in the exosome market due to improved healthcare infrastructure, efficient public policies, a enormous base of multinationals, and elevated knowledge of diagnostics and healthcare among individuals. A large number of government-funded research studies have been performed on the role of exosomal drugs in various types of cancers, including melanoma, breast cancer, pulmonary cancer, and pancreatic cancer. Companies such as Merck and Exosome Diagnostic have supported and collaborated on clinical trials in the United States with several universities such as Yale Univeristy and Micihigan State University. In addition, public financing supports these enterprises very well. Most of the research were performed for neoplasm.
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The exosomes market is highly competitive and consists of a number of major players. Companies such as Danaher Beckman Coulter Inc. , Diagenode Inc., Fujifilm Holdings Corporation, Hitachi Chemical Diagnostics Inc., Lonza, MBL International, Miltenyi Biotec, Novus Biologicals, Qiagen, Thermo Fisher Scientific Inc., among others, hold significant exosome market share.
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